Search on: OLIGORIBONUCLEOTIDE PROBES 
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Descriptor English:   Oligonucleotide Probes 
Descriptor Spanish:   Sondas de Oligonucleótidos 
Descriptor Portuguese:   Sondas de Oligonucleotídeos 
Synonyms English:   Oligodeoxyribonucleotide Probes
Oligoribonucleotide Probes  
Tree Number:   D13.444.600.601
D27.720.470.530.600.650
Definition English:   Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin. 
Indexing Annotation English:   usually no qualif; /drug eff /ultrastruct permitted
See Related English:   Nucleic Acid Hybridization
Oligonucleotide Array Sequence Analysis
 
History Note English:   89 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   23787 
Unique Identifier:   D015345 

Occurrence in VHL:
 

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